SS-31 50mg Vial

SS-31 (Elamipretide) is a synthetic mitochondria-targeted tetrapeptide investigated for its interaction with mitochondrial membranes and cardiolipin stabilization. It has been widely studied in cellular and preclinical models involving mitochondrial dysfunction and oxidative stress.

This presentation contains 50 mg of lyophilized SS-31 peptide, intended strictly for laboratory research purposes only.

Mechanism of Action (Research Context)

SS-31 is designed to selectively target the inner mitochondrial membrane, where it interacts with cardiolipin, a phospholipid essential for mitochondrial structural integrity and electron transport chain function.

Binding to cardiolipin has been observed to influence several mitochondrial processes, including:

• Stabilization of mitochondrial membrane structure
• Improved efficiency of electron transport chain activity
• Reduction of reactive oxygen species (ROS) generation
• Enhanced ATP production in experimental models

Through these interactions, SS-31 has been investigated in research involving mitochondrial bioenergetics and oxidative stress regulation.

Molecular Information

• Sequence: D-Arg-dimethylTyr-Lys-Phe-NH₂
• Peptide Class: Mitochondria-targeted tetrapeptide
• Primary Target: Cardiolipin within the inner mitochondrial membrane
• Molecular Weight: ~639.8 g/mol
• Alternative Name: Elamipretide

Presentation

• 50 mg SS-31
• Lyophilized sterile powder

Storage

• Store lyophilized vial at 2–8 °C
• Protect from light and moisture
• Refer to laboratory handling protocols for stability following reconstitution

Research Applications

• Mitochondrial function and bioenergetics studies
• Cardiolipin interaction and membrane stability research
• Oxidative stress and reactive oxygen species investigations
• Cellular models of mitochondrial dysfunction
• Experimental metabolic and aging-related pathway studies

FOR RESEARCH USE ONLY